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F-18 FLT
3'-deoxy-3'-[18F] fluorothymidine ([18F]FLT)

相關介紹

3'-deoxy-3'-[18F] fluorothymidine ([18F]FLT) can be phosphorylated by thymidine kinase and retained in highly proliferating cells, such as malignant cells. Clinical studies demonstrated the feasibility of [18F]FLT PET for quantifying cellular proliferation. [18F]FLT uptake has been shown to correlate with histologic assessment of proliferation by Ki-67 in breast, lung, and brain cancers. Hence, [18F]FLT PET can be utilized for diagnosis, staging, and the assessment of treatment response.
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